2025年

外科部

沈延盛

Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells

Molecular Cancer 2025; 24(1):1-18.

27.7

腫瘤醫學部/臨床醫學研究中心

蘇文彬

Redox disruption using electroactive liposome coated gold nanoparticles for cancer therapy

Nature Communications 2025;16:3253

14.7

腫瘤醫學部

顏家瑞

Enhanced Catalytic Cycle of Glucose Oxidation and Reactive Species with ROS and RHS Generation Mediated by Galvanic Engineering of Dual Atomic Sites on Covalent Organic Frameworks Demonstrating Synergistic Bimetal Tumor Treatment

Advanced Science 2025; 12(29):e00515.

14.1

內科部

林建中

Enhancing Lung Recovery: Inhaled Poly(lactic- co-glycolic) Acid Encapsulating FTY720 and Nobiletin for Lipopolysaccharide-Induced Lung Injury, with Advanced Inhalation Tower Technology

ACS Nano 2025;19(8):7634~7649

15.8

外科部

陳柏全/賴昭翰

Neoadjuvant radiotherapy vs up-front surgery for resectable locally advanced rectal cancer

JAMA Network Open 2025; 8(5):e259049.

10.5

臨床醫學研究中心

蘇鈺筑

Oncogenic RARγ isoforms promote head and neck cancer proliferation through vinexin-β mediated cell cycle acceleration and autocrine activation of EGFR signal

International Journal of Biological Sciences 2025; 21(1):1-16.

10.0

2024年

內科部
婦產部

許雅婷
沈孟儒

Tight junction protein cingulin variant is associated with cancer susceptibility by overexpressed IQGAP1 and Rac1-dependent epithelial-mesenchymal transition

Journal Of Experimental & Clinical Cancer Research 2024;43:65

11.3

外科部

沈延盛

Extracellular Vesicular Analysis of Glypican 1 mRNA and Protein for Pancreatic Cancer Diagnosis and Prognosis

Advanced Science 2024;11(11):2306373

15.1

Germline mutations of homologous recombination genes and clinical outcomes in pancreatic cancer: a multicenter study in Taiwan

Journal of Biomedical Science 2024;31(1):21

11.0

臨床醫學研究中心

李青記

Prompt antimicrobial therapy and source control on survival and defervescence of adults with bacteraemia in the emergency department: the faster, the better

Critical Care 2024;28(1):176

15.1

內科部

柯文謙

內科部

楊貳翔
鄭修琦

10-Day versus 14-day bismuth quadruple therapy for first-line eradication of Helicobacter pylori infection: a randomised, open-label, non-inferiority trial

EClinicalMedicine 2024;70:102529

15.1

腫瘤醫學部/臨床醫學研究中心

蘇文彬

Polymeric nano-formulation of spectrum selective RTK inhibitor strengthens anti-cancer effects via immune remodeling by endoplasmic reticulum stress-modulating mitochondrial metabolism

Nano Today 2024;54:102070

17.4

APLF facilitates interstrand DNA crosslink repair and replication fork protection to confer cisplatin resistance

Nucleic Acids Research  2024; 52(10):5676-5697

16.6

Harnessing the Power of Sugar-Based Nanoparticles: A Drug-Free Approach to Enhance Immune Checkpoint Inhibition Against Glioblastoma and Pancreatic Cancer

ACS Nano 2024; 18(42):28764-28781.

15.8

皮膚部

王德華

A point-of-care electrochemical biosensor for the rapid and sensitive detection of biomarkers in murine models with LPS-induced sepsis

Biosensors and Bioelectronics 2024;254:116202

12.6

皮膚部

許釗凱

TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts

Journal of Biomedical Science 2024; 31(1):12

11.0

Dominant dystrophic epidermolysis bullosa is associated with glycolytically active GATA3+ T helper 2 cells which may contribute to pruritus in lesional skin

British Journal of Dermatology  2024; 191(2):252-260

11.0

職業及環境醫學部

簡玉雯

Discrepancies in dengue burden estimates: a comparative analysis of reported cases and global burden of disease study, 2010–2019

Journal of Travel Medicine 2024; 31(4):taae069

25.7

內科部

王竣令

Global trends in non-susceptibility rates of Streptococcus pneumoniae isolates to ceftriaxone: Data from the Antimicrobial Testing Leadership and Surveillance (ATLAS) programme, 2016-21

International Journal of Antimicrobial Agents 2024;63(2):107072

10.8

林建佑

Cardiac events and survival in patients with EGFR-mutant non–small cell lung cancer treated with osimertinib

JAMA Network Open 2024; 7(12):e2448364.

10.5

婦產部

許耿福

梁玉玲

Adipocyte pyroptosis occurs in omental tumor microenvironment and is associated with chemoresistance of ovarian cancer

Journal of Biomedical Science 2024;31(1):62

11.0

2023年

內科部
婦產部

許雅婷
沈孟儒

Electrical Sympathetic Neuromodulation Protects Bone Marrow Niche and Drives Hematopoietic Regeneration during Chemotherapy

Small Methods 2023;7(6):e2201300

12.4

外科部

沈延盛

Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer

Nature Communications  2023;14(1):6692

16.6

外科部

沈延盛
趙盈瑞
王志榮

The experience of neoadjuvant chemotherapy versus upfront surgery in resectable pancreatic cancer: a cross sectional study

International Journal of Surgery 2023;109(9):2614~2623

15.3

腫瘤醫學部

蘇勇曄

內科部

王竣令
柯文謙

Geographic patterns of in vitro susceptibilities to tigecycline and colistin among worldwide isolates of Acinetobacter baumannii, Escherichia coli and Klebsiella pneumoniae: data from the Antimicrobial Testing Leadership and Surveillance (ATLAS) programme, 2016 to 2021

International Journal of Antimicrobial Agents 2023;62(3):106930

10.8

外科部

李榮順
王佳恩

Quantification of vessel separation using the carotid-jugular angle to predict the nerve origin of neck peripheral nerve sheath tumours: A pooled analysis of cases from the literature and a single-center cohort

International Journal of Surgery 2023;109(9):2704~2713

15.3

臨床醫學研究中心

蔡坤哲

Transthyretin attenuates TDP-43 proteinopathy by autophagy activation via ATF4 in FTLD-TDP

Brain 2023;146(5):2089~2106

15.255

內科部

薛俊盈

Improvement of Composite Kidney Outcomes by AKI Care Bundles: A Systematic Review and Meta-Analysis

Critical Care 2023;27(1):390

15.1

精神部

劉怡佳(職能治療師)

Occupational Evaluation of Community-Based Psychiatric Rehabilitation Outcomes in Individuals With Severe Mental Illnesses: A Ten-Year Retrospective Study

Asian Journal of Psychiatry 2023;81:103450

13.890

內科部
臨醫中心

李貽恒
林聖翔

Assessment of tyrosine kinase inhibitors and survival and cardiovascular outcomes of patients with non-small cell lung cancer in Taiwan

JAMA Network Open 2023;6(5):e2313824

13.360

Association of statin use with cancer- and noncancer-associated survival among patients with breast cancer in Asia

JAMA Network Open 2023;6(4):e239515

13.360

病理部

蔡慧頻(醫事檢驗師)

Acyclovir-resistant HSV-1 isolates among immunocompromised patients in southern Taiwan: Low prevalence and novel mutation

Journal of Medical Virology 2023;95(8):e28985

12.7

小兒部

何宗憲

 Developing magnetic barcode bead fluorescence assay for high throughput analyzing humoral responses against multiple SARS-CoV-2 variants

Biosensors and Bioelectronics 2023;241:115709

12.6

耳鼻喉部

張展旗

Single-sized N-functionality graphene quantum dot in tunable dual-modality near infrared–I/II illumination detection and photodynamic therapy under multiphoton nonlinear excitation

Biosensors and Bioelectronics 2023;241:115648

12.6

外科部

賴昭翰

Soluble CD93 lectin-like domain sequesters HMGB1 to ameliorate inflammatory diseases

Theranostics 2023;13(12):4059~4078

12.4

臨床醫學研究中心

洪澤民

Exosomal long noncoding RNA MLETA1 promotes tumor progression and metastasis by regulating the miR‑186‑5p/EGFR and miR‑497‑5p/IGF1R axes in non‑small cell lung cancer

Journal Of Experimental & Clinical Cancer Research 2023;42(1):283

11.3

MiR-455-5p suppresses PDZK1IP1 to promote the motility of oral squamous cell carcinoma and accelerate clinical cancer invasion by regulating partial epithelial-to-mesenchymal transition

Journal Of Experimental & Clinical Cancer Research 2023;42(1):40

11.3

內科部

王崇任

Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus

Journal of Biomedical Science 2023;30(1):78

11.0

復健部

連偉志

Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation

Bioengineering & Translational Medicine 2023;8(1):e10346

10.684

感染管制中心/內科部

李南瑤
翁子評

Integration of antimicrobial stewardship intervention with rapid organism identification improve outcomes in adult patients with bloodstream infections

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2023;56(1):57~63

10.273

內科部

鄭斌男

Interdependence of glycemic and lipid modulation in cured chronic hepatitis C patients by direct-acting antiviral agents

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2023;56(1):20~30

10.273

小兒部

沈靜芬
謝奇璋

Pre-existing humoral immunity and CD4+ T cell response correlate with cross-reactivity against SARS-CoV-2 Omicron subvariants after heterologous prime-boost vaccination

Clinical Immunology  2023;251:109342

10.190

外科部

陳柏全

HER2 amplification in colorectal cancer with brain metastasis: a propensity score matching study

European Journal of Cancer 2023;181:62~69

10.002

腫瘤醫學部

葉裕民
陳海雯

內科部

劉嚴文

HLA-Ehigh/HLA-Ghigh/HLA-IIlow Human iPSC-Derived Cardiomyocytes Exhibit Low Immunogenicity for Heart Regeneration

Advanced Healthcare Materials 2023;12(29):e2301186

10.0

2022年

外科部

沈延盛

Tumor‑associated macrophages promote resistance of hepatocellular carcinoma cells against sorafenib by activating CXCR2 signaling

Journal of Biomedical Science 2022;29(1):99

12.771

Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy

Theranostics 2022;12(1):340~361

11.556

內科部

柯文謙

Immunogenicity and safety of homologous and heterologous ChAdOx1-S and mRNA-1273 vaccinations in healthy adults in Taiwan

Journal of Clinical Virology 2022;150:105156

14.481

The emergence of Clostridioides difficile PCR ribotype 127 at a hospital in northeastern Taiwan

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(5):896~909

10.273

Trend in healthcare-associated infections due to vancomycin-resistant Enterococcus at a hospital in the era of COVID-19: more than hand hygiene is needed

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(6):1211~1218

10.273

內科部

蔡進相
柯文謙

Changing epidemiology of shigellosis in Taiwan, 2010-2019: an emerging threat to HIV-infected patients and men who have sex with men

Emerging Microbes & Infections 2022;11(1):498~506

19.568

內科部

李明吉
柯文謙

Species identification and antifungal susceptibility of uncommon blood yeast isolates

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(1):130~137

10.273

內科部

柯文謙
李仁傑
陳柏齡

Causes of death among dengue patients causes of death among hospitalized adults with dengue fever in Tainan, 2015: Emphasis on cardiac events and bacterial infections

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(2):207~214

10.273

腫瘤醫學部/臨床醫學研究中心

蘇文彬

Atomically dispersed golds on degradable zero-valent copper nanocubes augment oxygen driven Fenton-like reaction for effective orthotopic tumor therapy

Nature Communications 2022;13(1):7772

17.694

Polyaniline-Based Glyco-Condensation on Au Nanoparticles Enhances Immunotherapy in Lung Cancer

ACS Applied Materials ＆ Interfaces 2022;14(21):24144~24159

10.383

Chemical Structure and Shape Enhance MR Imaging Guided X-ray Therapy Following Marginative Delivery

ACS Applied Materials ＆ Interfaces 2022; 14(11):13056-13069

10.383

內科部

陳嫈文
陳柏齡

Risk of non-typhoidal Salmonella vascular infections is increased with degree of atherosclerosis and inflammation: A multicenter study in southern Taiwan

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(3):474~481

10.273

內科部

李南瑤
柯文謙

Respiratory etiological surveillance among quarantined patients with suspected lower respiratory tract infection at a medical center in southern Taiwan during COVID-19 pandemic

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(3):428~435

10.273

內科部

李南瑤

A multicenter cohort study of severe dengue and critically ill influenza patients with elevated cardiac troponin-I: Difference clinical features and high mortality

Travel Medicine and Infectious Disease 2022;47:102281

20.441

內科部

李南瑤
蔡文嘉
羅景霳

Antimicrobial treatment of monomicrobial phenotypic carbapenem-resistant Klebsiella pneumoniae bacteremia: Two are better than one

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(6):1219~1228

10.273

內科部

鄭斌男

Entecavir Prevents HBV Reactivation During Direct Acting Antivirals for HCV/HBV Dual Infection: A Randomized Trial

Clinical Gastroenterology and Hepatology 2022;20(12):2088~2808

13.576

眼科部

洪嘉鴻
蘇鈺宸

Comparison of Sodium-Glucose Cotransporter 2 Inhibitors vs Glucagonlike Peptide-1 Receptor Agonists and Incidence of Dry Eye Disease in Patients With Type 2 Diabetes in Taiwan

JAMA Network Open 2022;5(9):e2232584

13.366

精神部

陳柏熹

 Generational synaptic functions of GABAA receptor β3 subunit deteriorations in an animal model of social deficit

Journal of Biomedical Science 2022;29(1):51

12.771

泌尿部

胡哲源

Interruption of the long non-coding RNA HOTAIR signaling axis ameliorates chemotherapy-induced cachexia in bladder cancer

Journal of Biomedical Science 2022;29(1):104

12.771

內科部

王崇任

Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar hemorrhage

Journal of Biomedical Science 2022;29(1):62

12.771

腫瘤醫學部

蔡慧珍

PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation

Journal of Biomedical Science 2022;29(1):92

12.771

內科部

楊思雋

Economic analysis of exclusionary EGFR test versus up-front NGS for lung adenocarcinoma in high EGFR mutation prevalence areas

Journal of the National Comprehensive Cancer Network 2022;20(7):774~782

12.693

腫瘤醫學部

張光裕

SH3GLB1‑related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma

Journal Of Experimental & Clinical Cancer Research 2022;41(1):220

12.658

小兒部

張毓珊
林其和

Postnatal Dexamethasone Therapy Impairs Brown Adipose Tissue Thermogenesis and Autophagy Flux in Neonatal Rat Pups

Theranostics 2022;12(13):5803~5819

11.600

臨醫中心

蔡曜聲

臨床醫學研究中心

洪澤民

α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer

Theranostics 2022;12(3):1173~1186

11.556

小兒部
家庭醫學部

蔡孟哲
李芷婷

Reciprocal peer network processes on substance use and delinquent behavior in adolescence: Analysis from a longitudinal youth cohort study

International Journal of Mental Health and Addiction 2022;2022:1~14

11.555

精神部

陳柏熹

Associations among smartphone app-based measurements of mood, sleep and activity in bipolar disorder

Psychiatry Research 2022;310:114425

11.225

內科部

林峻宇

Time-dependent Analysis of Risk of New-onset Heart Failure among Patients with Polymyositis and Dermatomyositis

Arthritis and Rheumatology 2022;74(1):140~149

10.995

小兒部

何宗憲

Development of SARS-CoV-2 variant protein microarray for profiling humoral immunity in vaccinated subjects

Biosensors and Bioelectronics 2022;204:114067

10.618

精神部

陳高欽
楊延光

Striatal dopamine D2/3 receptors in medication-naïve schizophrenia: an [123I] IBZM SPECT study

Psychological Medicine 2022;52(14):3251~3259

10.592

小兒部

沈靜芬

Outbreak of respiratory syncytial virus subtype ON1 among children during COVID-19 pandemic in Southern Taiwan

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(6):1168~1179

10.273

小兒部

沈靜芬
劉清泉

The epidemiology, clinical characteristics, and macrolide susceptibility of Mycoplasma pneumoniae pneumonia in children in Southern Taiwan, 2019-2020

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(4):611~619

10.273

內科部

曾進忠

Escherichia coli FimH adhesins act synergistically with PapGII adhesins for enhancing establishment and maintenance of kidney infection

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(1):44~50

10.273

內科部

林威宏

Escherichia coli urinary tract infections: host age-related differences in bacterial virulence factors and antimicrobial susceptibility

微免與感染雜誌 Journal of Microbiology, Immunology and Infection 2022;55(2):249~256

10.273

病理部

蔡慧頻醫事檢驗師

Novel Software for High-level Virological Testing: Self-Designed Immersive Virtual Reality Training Approach

Journal Of Medical Internet Research 2023;25:e44538

7.4

Highly-specific aptamer targeting SARS-CoV-2 S1 protein screened on an automatic integrated microfluidic system for COVID-19 diagnosis

Analytica Chimica Acta 2023;1274:341531

6.2

RNA Interference Approach Is a Good Strategy against SARS-CoV-2

Viruses-Basel 2023;15(1):100

5.8

Simultaneous detection of SARS-CoV-2 and influenza A/B viruses on an electromagnetically-driven, integrated microfluidic system

Sensors and Actuators B: Chemical 2024; 410:135647.

8.0

藥劑部
內科部

鄭靜蘭藥師
莊喬雄醫師

Suboptimal outcomes and retreatment rate of patients with crohn’s disease affter forced discontinuation of biologics: a nationwide population-based study

Clinical Pharmacology & Therapeutics 2023;114(4):914~921

6.7

藥劑部

鄭靜蘭藥師

Comparative effectiveness of bevacizumab versus cetuximab in metastatic colorectal cancer patients without primary tumor resection

Cancers 2022;14(9):2118

6.6

Sex difference in heart failure risk associated with febuxostat and allopurinol in gout patients

Frontiers in Cardiovascular Medicine 2022;9:891606

5.8

病理部

陳怡伶醫事檢驗師

Enhancing diagnosis of T-cell lymphoma using non-recombined T-cell receptor sequences

Frontiers in Oncology 2022;12:1014132

5.7

藥劑部

黃千惠藥師
鄭靜蘭藥師

Association Between Risk of Clostridium difficile Infection and Duration of Proton Pump Inhibitor or H2-Receptor Antagonist Use in Hospitalized Patients

Infectious Diseases and Therapy 2024;13(2):373~383

5.4

臨床創新研發中心

蘇建州博士

護理部

馮瑞鶯

Health services utilization and cost of abusive head trauma in Taiwan: A population-based retrospective matched cohort study

Child Abuse & Neglect 2022;128:105603

學門排名4.5%

Patterns and trajectories of children’s maltreatment experiences in Taiwan: Latent transition analysis of a nationally representative longitudinal study

Child Abuse & Neglect  2023;135:105951

學門排名4.5%

Development of a disaster preparedness training program for community leaders: Evidence from Taiwan

International Journal of Disaster Risk Reduction 2024;108:104517

5.0

陳佳德

Cold Application in Pain and Anxiety Reduction following Chest Tube Removal: A Systematic Review and Meta-Analysis

Journal of Clinical Nursing 2023;32(3-4):574~583

學門排名3.2%

孫婉娜

Nurses’ Knowledge and Skills After Use of an Augmented Reality App for Advanced Cardiac Life Support Training: Randomized Controlled Trial

Journal Of Medical Internet Research 2024; 26:e57327.

5.8

復健部

徐秀雲

Effects of an assist-as-needed equipped Tenodesis-Induced-Grip Exoskeleton Robot (TIGER) on upper limb function in patients with chronic stroke

Journal of NeuroEngineering and Rehabilitation 2024;21(1):5

5.2